A65: ICD10 Code for Nonvenereal syphilis
A65 is the ICD10 code used for documenting Nonvenereal syphilis in clinical and billing records.

A65 refers to Nonvenereal syphilis, a group of bacterial infections caused by spirochetes. These conditions, while less commonly reported today, remain significant in certain global regions and require accurate ICD10 documentation for appropriate clinical care and epidemiological tracking. Correct usage of this code ensures standardized medical records and facilitates global health surveillance.
Symptoms
- Skin lesions – Ulcers, nodules, or discolored patches
- Fever – Recurrent in relapsing fevers or systemic infections
- Joint pain – Especially in yaws and nonvenereal syphilis
- Neurological symptoms – Possible in untreated advanced stages
- Headache – Common during febrile episodes
- Malaise – General body discomfort and fatigue
- Swollen lymph nodes – Present in many spirochetal infections
Diagnosis
Diagnosis of Nonvenereal syphilis typically includes clinical examination and laboratory confirmation. Blood smears, dark-field microscopy, or serologic tests such as VDRL and RPR are used to detect spirochetes. PCR and culture methods may help identify the specific species involved. In endemic areas, diagnosis may be largely clinical, with lab support used to confirm or differentiate the infection type.
ICD10 Code Usage
ICD10 code A65 is used across healthcare documentation systems, especially in cases involving spirochetal infections. It facilitates accurate tracking of disease prevalence and supports billing for diagnostic and therapeutic procedures. Public health organizations use these codes to monitor regional disease burdens and implement intervention programs.
Related Codes
FAQs
Q1: What is ICD10 code A65?
A: It refers to Nonvenereal syphilis, categorized under spirochetal bacterial infections in ICD10.
Q2: Are these infections still common?
A: While rare in developed countries, they remain endemic in tropical and low-resource regions.
Q3: Can these conditions be cured?
A: Yes, most respond well to antibiotics like penicillin if treated early.
Q4: Are these conditions contagious?
A: Yes, many are spread via skin contact, vector bites, or contaminated materials.
Q5: Is there a vaccine?
A: No vaccines exist, but prevention through hygiene and early treatment is effective.
Conclusion
ICD10 code A65 ensures that cases of Nonvenereal syphilis are documented accurately and managed appropriately. These rare but impactful infections require global awareness, especially in endemic regions. Consistent use of ICD10 codes helps support clinical care, guide treatment, and strengthen public health strategies worldwide.

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