G35: ICD10 Code for Multiple sclerosis
G35 is the ICD10 code used for documenting Multiple sclerosis in clinical and billing records.

G35 refers to Multiple sclerosis, a group of disorders characterized by damage to the myelin sheath that insulates nerve fibers in the central nervous system (CNS). This demyelination disrupts neural transmission and can result in varied neurological symptoms depending on the areas affected.
Symptoms
- Vision problems – Blurred or double vision, especially in MS (G35)
- Muscle weakness or stiffness – Often seen in G35 and G36 demyelination
- Fatigue – A common and debilitating symptom across all demyelinating diseases
- Coordination or balance issues – Typical of CNS involvement
- Numbness or tingling – Especially in limbs or face
- Bladder or bowel dysfunction – May occur in advanced or relapsing cases
- Cognitive changes – Including memory or attention problems in MS
Diagnosis
Diagnosis of Multiple sclerosis relies on MRI imaging of the brain and spinal cord, lumbar puncture (CSF analysis for oligoclonal bands), evoked potentials, and clinical history of relapsing/remitting or progressive symptoms. Early recognition is key for treatment planning.
ICD10 Code Usage
ICD10 code G35 is used by neurologists, general practitioners, rehabilitation specialists, and in multiple sclerosis clinics. It assists with documenting disease progression, therapy responses, insurance approval, and long-term disability care coordination.
Related Codes
- G36 – Other acute disseminated demyelination
- G37 – Other demyelinating diseases of central nervous system
FAQs
Q1: What is ICD10 code G35?
A: It represents Multiple sclerosis, a neurological condition involving damage to myelin in the CNS, impairing signal transmission between the brain and body.
Q2: Is multiple sclerosis (G35) progressive?
A: MS can be relapsing-remitting, secondary progressive, or primary progressive depending on the clinical course.
Q3: What causes demyelinating diseases?
A: They can be autoimmune (like MS), post-infectious (G36), or idiopathic; some are linked to other systemic illnesses or vaccinations.
Q4: How are these conditions treated?
A: Disease-modifying therapies (DMTs), corticosteroids, symptom management medications, and physical therapy.
Q5: Who manages these conditions?
A: Neurologists, MS specialists, physical and occupational therapists, and sometimes immunologists or rheumatologists.
Conclusion
ICD10 code G35 is critical for the proper identification, classification, and long-term care planning of patients with Multiple sclerosis. It supports therapy decisions, access to disability resources, and ongoing monitoring of neurological health.

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