M04: ICD10 Code for Autoinflammatory syndromes

M04 is the ICD10 code used for documenting Autoinflammatory syndromes in rheumatology and musculoskeletal care.

M04 - Autoinflammatory syndromes

M04 refers to Autoinflammatory syndromes, covering inflammatory, autoimmune, crystal deposition, or systemic disease-associated joint disorders. These conditions vary in onset, chronicity, and tissue damage severity, requiring early detection and management to preserve function.

Symptoms

  • Joint swelling and stiffness – Core feature of most inflammatory arthritides
  • Morning stiffness – Especially severe in rheumatoid arthritis (M05, M06)
  • Painful flares – Seen in gout (M10, M1A) and crystal arthropathies (M11)
  • Systemic symptoms – Fever, rash, or fatigue in juvenile arthritis (M08) and autoinflammatory syndromes (M04)
  • Joint deformities – Chronic progression may lead to erosion and dysfunction

Diagnosis

Diagnosis of Autoinflammatory syndromes combines clinical evaluation, rheumatoid factor and anti-CCP antibodies (for RA), serum uric acid levels (for gout), joint aspiration, imaging (X-ray, MRI), and sometimes genetic or systemic workup depending on suspected etiology.

ICD10 Code Usage

ICD10 code M04 is used by rheumatologists, orthopedic surgeons, pediatricians (for M08), and internal medicine specialists. It supports insurance documentation for immunosuppressive therapies, biologics, joint replacement surgeries, and disability assessment.

Related Codes

FAQs

Q1: What is ICD10 code M04?
A: It refers to Autoinflammatory syndromes, which includes various inflammatory, autoimmune, or crystal-induced joint diseases affecting function and mobility.

Q2: How is chronic gout (M1A) different from acute gout (M10)?
A: M10 describes acute painful flares, while M1A documents longstanding, often deforming gout with tophi deposits and persistent joint involvement.

Q3: What distinguishes M05 and M06 rheumatoid arthritis?
A: M05 includes rheumatoid factor-positive RA, while M06 includes seronegative variants and other RA presentations.

Q4: What is enteropathic arthropathy (M07)?
A: Joint inflammation associated with inflammatory bowel diseases like Crohn’s disease or ulcerative colitis.

Q5: Who manages these disorders?
A: Primarily rheumatologists, with support from orthopedic surgeons, internists, pediatricians, and physical therapists.

Conclusion

ICD10 code M04 ensures accurate classification and proactive treatment of Autoinflammatory syndromes, facilitating better management of joint inflammation, prevention of deformities, and improvement of patient quality of life.

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