M46: ICD10 Code for Other inflammatory spondylopathies
M46 is the ICD10 code used for documenting Other inflammatory spondylopathies in orthopedic, rheumatology, and spine care settings.

M46 refers to Other inflammatory spondylopathies, a category of spinal disorders primarily characterized by inflammation, degeneration, or abnormal fusion of the vertebrae. These conditions can severely impact spinal flexibility, cause chronic pain, and contribute to neurological complications if untreated.
Symptoms
- Chronic back pain and stiffness – Hallmark of ankylosing spondylitis (M45) and spondylosis (M47)
- Reduced spinal mobility – Seen across inflammatory and degenerative spondylopathies
- Radiating limb pain – Due to nerve root compression (common in M47, M48)
- Postural changes – Kyphotic posture in advanced ankylosing spondylitis
- Fatigue and systemic inflammation – In inflammatory spondylopathies (M46)
Diagnosis
Diagnosis of Other inflammatory spondylopathies involves clinical assessment, spinal X-rays, MRI for early inflammation detection, HLA-B27 genetic testing (for ankylosing spondylitis), and evaluation of neurological function if spinal cord compression is suspected.
ICD10 Code Usage
ICD10 code M46 is used by rheumatologists, orthopedic surgeons, spine specialists, and rehabilitation physicians for documenting spinal inflammatory, degenerative, or secondary disease-related changes.
Related Codes
- M45 – Ankylosing spondylitis
- M47 – Spondylosis
- M48 – Other spondylopathies
- M49 – Spondylopathies in diseases classified elsewhere
FAQs
Q1: What is ICD10 code M46?
A: It refers to Other inflammatory spondylopathies, encompassing spinal diseases marked by inflammation, degeneration, or secondary disease involvement affecting the vertebrae and intervertebral discs.
Q2: What distinguishes M45 from M47?
A: M45 (Ankylosing spondylitis) is an autoimmune inflammatory disease leading to spinal fusion, while M47 (Spondylosis) refers to degenerative disc and joint changes typically due to aging or wear-and-tear.
Q3: How are inflammatory spondylopathies (M46) different?
A: M46 includes various spinal inflammations not classified specifically as ankylosing spondylitis, such as discitis or non-specific vertebral osteitis.
Q4: What is treated under M48?
A: M48 captures conditions like spinal stenosis, collapsed vertebrae, and other complex spondylopathies not elsewhere specified.
Q5: What is the role of imaging in diagnosis?
A: Imaging is crucial for detecting early inflammatory changes, assessing spinal alignment, nerve involvement, and evaluating the extent of degeneration or structural damage.
Conclusion
ICD10 code M46 ensures accurate diagnosis and tracking of Other inflammatory spondylopathies, enabling targeted management strategies to preserve spinal function, relieve symptoms, and improve long-term quality of life in affected patients.

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