R22: ICD10 Code for Localized swelling, mass and lump of skin and subcutaneous tissue
R22 is the ICD10 code used for documenting Localized swelling, mass and lump of skin and subcutaneous tissue involving skin sensations, rashes, swellings, and other changes.

R22 refers to Localized swelling, mass and lump of skin and subcutaneous tissue, covering various nonspecific skin abnormalities such as altered sensations (tingling, numbness), rashes, localized swellings, and unexplained skin discolorations without a confirmed disease diagnosis.
Symptoms
- Numbness or tingling – Common in disturbances of skin sensation (R20)
- Generalized or localized rash – Seen in R21
- Noticeable lump or swelling under the skin – Indicative of R22
- Skin color changes (paleness, redness) – Associated with R23
Diagnosis
Diagnosis is based on clinical examination, patient history, skin biopsy (if necessary), blood tests to rule out infections or allergies, and imaging if an underlying mass is suspected.
ICD10 Code Usage
ICD10 code R22 is widely used in dermatology, primary care, and emergency settings for documenting skin symptoms pending final diagnosis, billing evaluations, and tracking symptom evolution over time.
Related Codes
- R20 – Disturbances of skin sensation
- R21 – Rash and other nonspecific skin eruption
- R23 – Other skin changes
FAQs
Q1: What is ICD10 code R22?
A: It documents Localized swelling, mass and lump of skin and subcutaneous tissue, referring to nonspecific or unexplained skin-related findings.
Q2: Is a rash always due to an allergy?
A: Not necessarily; infections, autoimmune conditions, or unknown causes can trigger rashes.
Q3: When should swelling under the skin be evaluated?
A: Persistent, painful, or rapidly growing lumps should be promptly assessed by a physician.
Q4: Can numbness in the skin be temporary?
A: Yes, it can result from temporary nerve compression, but persistent symptoms need evaluation.
Q5: What skin changes are considered urgent?
A: Sudden widespread rash, severe swelling, or skin discoloration with breathing difficulty requires emergency care.
Conclusion
ICD10 code R22 enables healthcare providers to systematically document Localized swelling, mass and lump of skin and subcutaneous tissue, ensuring proper evaluation, early intervention, and appropriate management of dermatologic symptoms.

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