D71: ICD10 Code for Functional disorders of polymorphonuclear neutrophils
D71 is the ICD10 code used for documenting Functional disorders of polymorphonuclear neutrophils in clinical and billing records.

D71 refers to Functional disorders of polymorphonuclear neutrophils, a category of hematologic disorders affecting white blood cells, spleen function, or oxygen-carrying capacity. These conditions can result from genetic mutations, infections, immune dysfunction, or secondary effects of other diseases and treatments like chemotherapy.
Symptoms
- Increased infections – Particularly in neutropenia or WBC dysfunction
- Fever – Often the first sign in immunocompromised individuals
- Enlarged spleen – Seen in many splenic and lymphoreticular disorders
- Blue-tinged skin or lips – A sign of methemoglobinemia
- Fatigue – Common with blood oxygenation issues or systemic inflammation
- Easy bruising or bleeding – If spleen involvement reduces platelet counts
- Pallor or poor circulation – Seen in severe systemic blood disorders
Diagnosis
Diagnosis of Functional disorders of polymorphonuclear neutrophils involves a combination of CBC with differential, peripheral blood smear, bone marrow biopsy, spleen ultrasound, methemoglobin levels, and sometimes genetic or immunologic testing. The cause and severity guide treatment and monitoring.
ICD10 Code Usage
ICD10 code D71 is used across internal medicine, hematology, oncology, and infectious disease. It supports accurate coding for immunodeficiencies, white cell abnormalities, spleen diseases, and systemic hematologic conditions linked to other diagnoses.
Related Codes
- D70 – Neutropenia
- D72 – Other disorders of white blood cells
- D73 – Diseases of spleen
- D74 – Methemoglobinemia
- D75 – Other and unspecified diseases of blood and blood-forming organs
- D76 – Other specified diseases with participation of lymphoreticular and reticulohistiocytic tissue
- D77 – Other disorders of blood and blood-forming organs in diseases classified elsewhere
FAQs
Q1: What is ICD10 code D71?
A: This code documents Functional disorders of polymorphonuclear neutrophils, a type of white blood cell or spleen disorder in clinical records.
Q2: What causes these conditions?
A: Causes include congenital immune defects, chemotherapy, infections, inflammatory diseases, or toxins.
Q3: Are these conditions serious?
A: Yes, they can predispose to life-threatening infections or systemic complications if unmanaged.
Q4: How are they treated?
A: Antibiotics, immunoglobulin therapy, granulocyte colony-stimulating factors (G-CSF), oxygen therapy, or splenectomy depending on the condition.
Q5: Who manages these disorders?
A: Hematologists, immunologists, infectious disease experts, and sometimes oncologists or surgeons.
Conclusion
ICD10 code D71 plays a key role in diagnosing and tracking Functional disorders of polymorphonuclear neutrophils. Accurate classification ensures appropriate evaluation, risk monitoring, and individualized treatment plans for these complex and often immunologically significant disorders.

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