D76 refers to Other specified diseases with participation of lymphoreticular and reticulohistiocytic tissue, a category of hematologic disorders affecting white blood cells, spleen function, or oxygen-carrying capacity. These conditions can result from genetic mutations, infections, immune dysfunction, or secondary effects of other diseases and treatments like chemotherapy.

Symptoms

Increased infections – Particularly in neutropenia or WBC dysfunction
Fever – Often the first sign in immunocompromised individuals
Enlarged spleen – Seen in many splenic and lymphoreticular disorders
Blue-tinged skin or lips – A sign of methemoglobinemia
Fatigue – Common with blood oxygenation issues or systemic inflammation
Easy bruising or bleeding – If spleen involvement reduces platelet counts
Pallor or poor circulation – Seen in severe systemic blood disorders

Diagnosis

Diagnosis of Other specified diseases with participation of lymphoreticular and reticulohistiocytic tissue involves a combination of CBC with differential, peripheral blood smear, bone marrow biopsy, spleen ultrasound, methemoglobin levels, and sometimes genetic or immunologic testing. The cause and severity guide treatment and monitoring.

ICD10 Code Usage

ICD10 code D76 is used across internal medicine, hematology, oncology, and infectious disease. It supports accurate coding for immunodeficiencies, white cell abnormalities, spleen diseases, and systemic hematologic conditions linked to other diagnoses.

Related Codes

FAQs

Q1: What is ICD10 code D76?
A: This code documents Other specified diseases with participation of lymphoreticular and reticulohistiocytic tissue, a type of white blood cell or spleen disorder in clinical records.

Q2: What causes these conditions?
A: Causes include congenital immune defects, chemotherapy, infections, inflammatory diseases, or toxins.

Q3: Are these conditions serious?
A: Yes, they can predispose to life-threatening infections or systemic complications if unmanaged.

Q4: How are they treated?
A: Antibiotics, immunoglobulin therapy, granulocyte colony-stimulating factors (G-CSF), oxygen therapy, or splenectomy depending on the condition.

Q5: Who manages these disorders?
A: Hematologists, immunologists, infectious disease experts, and sometimes oncologists or surgeons.

Conclusion

ICD10 code D76 plays a key role in diagnosing and tracking Other specified diseases with participation of lymphoreticular and reticulohistiocytic tissue. Accurate classification ensures appropriate evaluation, risk monitoring, and individualized treatment plans for these complex and often immunologically significant disorders.